Carolina Solange Ilkow,Fabrice Le Boeuf,John Cameron Bell,Jean-Simon Diallo,Rozanne Arulanandam
申请号：
US14898083
公开号：
US10066214B2
申请日:
2014.06.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
