Carolina Solange ILKOW,Fabrice LE BOEUF,John Cameron BELL,Jean-Simon DIALLO,Rozanne ARULANANDAM
申请号:
US15919554
公开号:
US20180237753A1
申请日:
2018.03.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.