Robert Forbes Anderson,Jeffery Bruce Smaill,Adam Vorn Patterson,Amir Ashoorzadeh,David Francis Ackerley,Janine Naomi Copp,Alexandra Marie Mowday,Elsie May Williams,Christopher Paul Guise,Cameron Koch
申请号：
US14368261
公开号：
US20150010474A1
申请日:
2012.12.21
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention relates generally to compounds and methods for imaging and/or selective ablation of nitroreductase-expressing cells and/or biological agents. More particularly, although not exclusively, the invention provides compounds that are selectively metabolised by bacterial nitroreductases and are substantially insensitive to metabolism under oxic or hypoxic conditions by human nitroreductase enzymes.
