PROBLEM TO BE SOLVED: To provide an agent for preventing or ameliorating lifestyle-related diseases.SOLUTION: An agent for preventing or ameliorating lifestyle-related disease contains a Jerusalem artichoke (component A) and a metabolite extract (component B) extracted from a metabolite obtained by subjecting mixed microorganisms including a plurality of lactic acid bacteria to symbiosis culture at a medium including soybeans and black soybeans, as an active component. A content ratio (A/B) of the component A and the component B in an active ingredient is desirably 1.5-3.5 in terms of a dry weight.