Jay A. Berzofsky;Thomas A. Waldmann;Liyanage P. Perera;Sang-Kon Oh
发明人:
Liyanage P. Perera,Thomas A. Waldmann,Sang-Kon Oh,Jay A. Berzofsky
申请号：
US10538974
公开号：
US08663622B2
申请日:
2003.12.15
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention is directed to compositions capable of augmenting the immunogenicity of a vaccine. The composition, or adjuvant, is administered to a mammal in need thereof in sequential or concurrent combination with a vaccine antigen. In one preferred aspect, the adjuvant is provided in the form of a recombinant poxvirus vector, such as a vaccinia virus vector, which comprises a nucleic acid sequence encoding IL-15.
