AS REPRESENTED BY THE SECRETARY;THE GOVERNMENT OF THE UNITED STATES OF AMERICA; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
PERERA, LIYANGE P.,WALDMANN, THOMAS A.,OH, SANG-KON,BERZOFSKY, JAY A.
申请号:
CA2510309
公开号:
CA2510309C
申请日:
2003.12.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention is directed to compositions capable of augmenting theimmunogenicity of a vaccine. The composition, or adjuvant, is administered toa mammal in need thereof in sequential or concurrent combination with avaccine antigen. In one preferred aspect, the adjuvant is provided in the formof a recombinant poxvirus vector, such as a vaccinia virus vector, whichcomprises a nucleic acid sequence encoding IL-15.