Various embodiments of a method of producing [SOLUTION] The sustained-release microparticle method of producing present invention relates to sustained-release fine particles is described. In one embodiment, the method includes forming a dispersed phase of the active agent in the polymer, to form a fine particle dispersion was mixed with the continuous phase to dispersed phase. The method includes the step of adding a diluent composition a certain amount of fine particle dispersion further. That the various embodiments for producing sustained-release particles with a diluent composition of varying amounts, to modify the release rate of the sustained-release fine particles on the particular active agent is found here. [Selection] Figure Figure 1【課題】徐放性微粒子を製造する方法【解決手段】徐放性微粒子を製造する方法の様々な実施態様が記載される。一つの実施態様において、本方法は、ポリマー中の活性剤の分散相を形成し、分散相を連続相と混合して微粒子分散系を形成する工程を含む。本方法はさらに微粒子分散系に一定量の希釈組成物を添加する工程を含む。様々な量の希釈組成物を用いた徐放性微粒子を製造するための様々な実施態様が、特定の活性剤に関する徐放性微粒子の放出速度を変更することがここに見出される。【選択図】図1
