Heat, moisture, and to protect against oxidation, The present invention relates to a method of producing such fine particles and a bioactive agent. [MEANS FOR SOLVING PROBLEMS] biologically active substances, aggregation agents, emulsifying agents, and particles comprising the solid fat is disclosed. Method of producing microparticles containing a biologically active agent aggregation, covered in two layers of solid fat and emulsifiers are also disclosed. [Selection] Figure Figure 1【課題】本発明は、生物活性物質を熱、湿度、及び酸化から保護するための、微粒子及びかかる微粒子の製造方法に関する。【解決手段】生物活性物質、凝集剤、乳化剤、及び固体脂肪を含む微粒子が開示される。固体脂肪及び乳化剤の二重層を被せた凝集生物活性物質を含む微粒子の製造方法も開示される。【選択図】図1