CRYSTALLINIC FORMS OF SUPRAMOLECULATED TRINATRIUM COMPLEX, INCLUDING VALSARTAN AND AHU-377, AND PROCEDURES THEREOF

• 收藏
• 分享

专利权人:

Crystal Pharmatech Co., Ltd.;Suzhou Pengxu Pharmatech Co., Ltd.

发明人:

CHEN, Minhua,ZHANG, Yanfeng,YANG, Chaohui,ZHANG, Xiaoyu,LI, Jiaoyang,WANG, Peng,LI, Pixu

申请号：

DK15843405

公开号：

DK3229799T3

申请日:

2015.12.08

申请国别(地区):

DK

年份:

2019

代理人:

摘要：

Novel crystalline Form I of trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3'-methyl-2'- (pentanoyl {2"-(tetrazol-5-ylate)biphenyl-4'-ylmethyl}amino)butyrate] hydrate, methods for its preparation, pharmaceutical compositions comprising the new form, and use of them for treating or delaying progression or onset of diseases or disorders related to activity of angiotensin receptor 1 (AT1) blockage and neprilysin (NEP) inhibition, such as heart failure, are disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/