UNIVERSITY OF IOWA RESEARCH FOUNDATION;THE UNIVERSITY OF KANSAS
发明人:
YAN, Ziying,ENGELHARDT, John F. F,QIU, Jianming,邱建明,嚴子英,約翰‧,‧恩格爾哈特
申请号:
HK16105979.6
公开号:
HK1217916A
申请日:
2016.05.25
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The invention provides an isolated chimeric virus comprising bocavirus capsid protein, e.g., an isolated chimeric virus comprising human bocavirus capsid protein, and a recombinant adeno-associated viral (AAV) genome, an isolated recombinant bocavirus (rBoV) comprising human bocavirus capsid protein and a recombinant Boy genome, and uses therefor, for example, in gene therapy for diseases in a mammal including diseases with aberrant expression of an endogenous gene product.