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Crystalline active ingredient microparticles, method for producing the same and use thereof in drugs
专利权人:
Sabine Gliesing;Detlef Grawe;Robert Eilers
发明人:
Detlef Grawe,Sabine Gliesing,Robert Eilers
申请号:
US13058168
公开号:
US09173843B2
申请日:
2009.06.30
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method for producing highly crystalline and stable microparticles of an active substance with a very narrow size distribution. The microparticles being crystallized out of a suspension made of primary particles of the active substance, a solution of the active substance, a non-solvent for the active substance and inert formed pieces. The resulting microparticles hare are highly stable largely independent of the physiochemical properties of the active substance and can be especially suitable for fast release dosage forms of pharmaceuticals.
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中国工程科技知识中心
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