LIM, HYUNG KYU,林亨奎,KIM, HYUN UK,金賢煜,LEE, MI KYOUNG,李美慶,LEE, JONG SOO,李鍾守,BAE, SUNG MIN,裴城敏,KWON, SE CHANG,權世昌
申请号：
HK15104957.6
公开号：
HK1204291A
申请日:
2015.05.26
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
The present invention relates to a liquid formulation of a combination of long-acting insulin and insulinotropic peptide, comprising insulin which is a physiologically active peptide, insulinotropic peptide, and albumin-free stabilizer, wherein the stabilizer comprises a buffer, a sugar alcohol, a non-ionic surfactant, and an isotonic agent and a method for preparing the liquid formulation. The liquid formulation of the present invention does not contain a human serum albumin and potentially toxic factors to the body, and thus it has excellent storage stability for insulin conjugate and insulinotropic peptide conjugate at high concentration, without a risk of viral contamination.
