SIEBEL, SARA IVA,PASCUA, EDWARD DERRICK,LIN, CHIA-YANG,CHAPARRO RIGGERS, JAVIER FERNANDO
申请号：
CA2859472
公开号：
CA2859472A1
申请日:
2012.12.10
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention provides antagonizing antibodies that bind to growth hormone receptor (GHR). The invention further relates to therapeutic methods for use of these antibodies to reduce IGF-1 levels and/or for the treatment and/or prevention of diseases associated with excessive IGF-1, including treatment of acromegaly, gigantism, cancer, diabetic nephropathy, arthritis, and lung inflammation.
