PROBLEM TO BE SOLVED: To provide an orally disintegrable tablet having suitably balanced oral disintegration rate and tablet hardness.SOLUTION: The orally disintegrable tablet is obtained by subjecting a mixture of fine particles containing a medicine or coated medicine and an auxiliary component for tablets to wet granulation using a starch water suspension heat-treated at ≥45°C and <63°C, mixing the obtained granule with at least a lubricant and compression molding the mixture.COPYRIGHT: (C)2012,JPO&INPIT【課題】口腔内崩壊速度と錠剤硬度が最適にバランスされた口腔内崩壊錠を提供する。【解決手段】薬物またはコーティングされた薬物含有微粒子と錠剤用補助成分との混合物を45℃以上63℃未満の温度で加熱処理したデンプン水懸濁液を用いて湿式造粒し、得られた造粒物に少なくとも滑沢剤を混合して圧縮成形してなる口腔内崩壊錠。【選択図】なし
