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DÉRIVÉS DE PIPÉRIDINE
专利权人:
F.HOFFMANN-LA ROCHE AG
发明人:
申请号:
EP11702848.0
公开号:
EP2536710B1
申请日:
2011.02.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention relates to compounds of formula where hetaryl I, hetaryl II, R1, R2, R3, R4, m, n, and o are as defined in the specification or to pharmaceutically active acid addition salts thereof. The compounds of formula I are modulators for amyloid beta and thus may be useful for the treatment or prevention of a disease associated with the deposition of beta-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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