КАТШЕЛЛ Нил С. (US),ГЕЙДЖ Дженнифер Линн (US),УИЛЕР Томас Нил (US),ЛИТТЛ Томас Л. (US)
申请号：
RU2012143610/04
公开号：
RU2012143610A
申请日:
2011.03.10
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A compound having the following formula (I): or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, wherein: A is: or R is C1-6alkyl, Haloalkyl, Caraalkyl, aryl, - (CH) O (CH) CH or - ( CH) N (CH)； R is (i) substituted or unsubstituted aryl or (ii) substituted or unsubstituted heterocyclyl； R is substituted or unsubstituted aryl； R is hydrogen, C1-6alkyl or Haloalkyl； n is 1, 2, 3, 4, 5 or 6； and m is 0, 1, 2, 3, 4, 5, or 6.2. The compound according to claim 1, where the compound has the following structure (I-A): 3. The compound according to claim 1, where the compound has the following structure (I-B): 4. The compound according to claim 1, where the compound has the following structure (I-C): 5. The compound according to claim 1, where the compound has the following structure (I-D): 6. The compound according to claim 1, where the compound has the following structure (I-E): 7. The compound according to claim 1, where the compound has the following structure (I-F): 8. The compound according to claim 1, where the compound has the following structure (I-G): 9. The compound according to claim 1, where the compound has the following structure (I-H): 10. The compound according to claim 1, where the compound has the following structure (I-I): 11. A compound according to claim 1, wherein R4 is hydrogen. A compound according to claim 1, wherein R1 is C1-6 alkyl. The compound of claim 12, wherein R4 is methyl. A compound according to claim 1, wherein R1 is C1-6alkyl. The compound of claim 14, wherein R4 is methyl. The compound of claim 14, wherein R is ethyl. 17. A compound according to claim 1, wherein R1 is substituted or unsubstituted phenyl. 18. The compound of claim 17, wherein R1 is substituted phenyl. 19. The compound of claim 18, wherein R4 is 4-bromo-3,5-dimethoxyphenyl. The compound of claim 18, wherein R4 is 4-chloro-3,5-dimethoxy1. Соединение, имеющее следующую формулу (I):или его фармацевтически приемлемая соль, стереоизомер, сольват
