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PHARMACEUTICAL COMPOSITION CONTAINING ARBIDOL IN THE FORM OF PHOSPHOLIPID NANOPARTICLES
专利权人:
Alexandr Ivanovich Archakov
发明人:
Alexandr Ivanovich Archakov,Mariya Kirillovna Guseva,Vasily Fedorovich Uchaykin,Olga Mikhaylovna Ipatova,Yury Fedorovich Dochshitsin,Yelena Georgiyevna Tikhonova,Natalya Velorikovna Medvedeva,Vladimir
申请号:
US13266843
公开号:
US20120052099A1
申请日:
2010.04.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to the fields of medicine and pharmacology and concerns a storage-stable composition made up of nanoparticles which are based on vegetable phospholipids and contain the antiviral drug Arbidol. The aim of the present invention is to develop a non-fatty phospholipid composition of Arbidol in which the micellar and liposomal particles have an average diameter of 8-25 nm, and which has low toxicity, can be stored for long periods and is capable of transporting the medicinal agent in the body and ensuring the high bioaccessibility of the agent. This aim is achieved by a phospholipid composition of Arbidol in the form of phospholipid nanoparticles with a size of 8-25 nm, which contains phosphatidylcholine, maltose and Arbidol in the following component ratio: 20-43 mass % phosphatidylcholine 55-78 mass % maltose 2-8 mass % Arbidol.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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