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Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
负责人:
关键词:
cancer protein target enabling package disease structure neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
DOI:
doi:10.5281/zenodo.1287260
摘要:
via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIMK1
Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
负责人:
关键词:
cancer protein target enabling package disease structure neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
DOI:
doi:10.5281/zenodo.1241027
摘要:
via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIMK1
Human LIM domain kinase 1 (LIMK1), kinase domain; A Target Enabling Package
负责人:
关键词:
cancer protein target enabling package disease structure neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
DOI:
doi:10.5281/zenodo.1219706
摘要:
via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIMK1
Data from: Molecular phylogenetics unveils the ancient evolutionary origins of the enigmatic fairy armadillos
负责人:
关键词:
Chlamyphorinae;Dasypodidae;Chlamyphorus truncatus;Xenarthra;Calyptophractus retusus
DOI:
doi:10.5061/dryad.38m4p
摘要:
] and NADH dehydrogenase 1 [MT-ND1]) and two nuclear exons (breast cancer 1 early onset exon 11 [BRCA1] and von Willebrand factor exon 28 [VWF]). Phylog
SKN-1 coordination of stress adaptation, metabolism, and resource allocation in Caenorhabditis elegans
负责人:
关键词:
Molecular Biology SKN-1 Nrf2 Asdf metabolism stress response resource allocation lipids high carbohydrate diet ALH-6
DOI:
doi:10.25549/usctheses-c40-260305
摘要:
ortant for diseases such as obesity and cancer, which characteristically have metabolic dysfunction. C. elegans are exceptionally well poised to handle
Data from: How innovative are new drugs launched in the UK? A retrospective study of new drugs listed in the British National Formulary (BNF) 2001
负责人:
关键词:
time trends;Innovation;New drug launches;pharmaceuticals
DOI:
doi:10.5061/dryad.pd670
摘要:
w biological drugs, categorised by degree of innovativeness according to published criteria that incorporate both clinical usefulness and the nature
Data from: NF-?B oscillations translate into functionally related patterns of gene expression
负责人:
关键词:
mouse embryo fibroblasts;Mus musculus;TNF-alpha;Pulsed stimulation;gene expression
DOI:
doi:10.5061/dryad.j62n1
摘要:
s in inflammation and cancer, displays oscillations whose biological advantage remains unclear. Recent work indicated that NF-?B displays sustained oscillations tha
Data from: Generalized selection to overcome innate immunity selects for host breadth in an RNA virus
负责人:
关键词:
Parasitism;Selection - Experimental;Adaptation;Fitness;Population Biology
DOI:
doi:10.5061/dryad.p9q57
摘要:
viral fitness in unselected human cancer cells of differing innate immunity, we confirmed that HeLa-adapted populations were specialized for innate immune

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