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A novel role for the 3\u2032-5\u2032 exoribonuclease Dis3L2 in controlling cell proliferation and tissue growth
- 负责人：
- 关键词：
- Biochemistry Cell Biology Genetics Molecular Biology 69999 Biological Sciences not elsewhere classified Developmental Biology
- DOI：
- doi:10.6084/m9.figshare.3830103
- 摘要：
- ssive cell proliferation can lead to diseases such as cancer. We have shown that the exoribonuclease Dis3L2 is required for the correct regulation of prolifer
Phylogenetic analysis and virulence determinant of the host-adapted Staphylococcus aureus<\/i> lineage ST188 in China
- 负责人：
- 关键词：
- Ecology Microbiology 59999 Environmental Sciences not elsewhere classified 69999 Biological Sciences not elsewhere classified Cancer 110309 Infectious Diseases Plant Biology 60506 Virology
- DOI：
- doi:10.6084/m9.figshare.7937831
- 摘要：
- demonstrated that ST188 might evolve from livestock, and there was no significant genomic or virulence difference between ST188 isolated from livestock
Data from: Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.44j0zpc9v
- 摘要：
- preclinical pharmacology data support its therapeutic potential in CDK9- or CDK2-dependent cancers and as a rational combination with BCL2 inhibi
Data from: Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma
- 负责人：
- DOI：
- doi:10.5061/dryad.10m4k6q
- 摘要：
- . Significantly enriched gene ontology biological process terms included RNA processing, non-coding RNA processing and phosphodiester bond hydrolysis
Data from: Synthesis of gypsogenin derivatives with capabilities to arrest cell cycle and induce apoptosis in human cancer cells
- 负责人：
- DOI：
- doi:10.5061/dryad.35j3j
- 摘要：
- e found to be much lower than those of the other derivatives and parent compound. These compounds were submitted to an extensive biological testing and proved
Sparks Et Al, Heterogeneity In Tumor Chromatin-Doxorubicin Binding Revealed By In Vivo Fluorescence Lifetime Imaging Confocal Endomicroscopy: In Vivo
- 负责人：
- DOI：
- doi:10.5281/zenodo.1249022
- 摘要：
- then peritoneal tumors were exposed by minor surgery and inspected with the CEM.All animal model procedures were approved by The Francis Crick Institute Biological
Data from:A computational study of cancer hyperthermia based on vascular magnetic nanoconstructs
- 负责人：
- DOI：
- doi:10.5061/dryad.20c5c
- 摘要：
- and heat transport in biological tissues. The model is defined at the scale of the tumour microenvironment and an advanced computational scheme called the embedded
Data from: Aneuploidy causes non-genetic individuality
- 负责人：
- DOI：
- doi:10.5061/dryad.30mv0
- 摘要：
- gene copy number imbalances, suggesting that subtle changes in gene expression impact the robustness of biological networks and cause alternate behaviors
Additional file 1: Table S1. of Loss of maternal ANNEXIN A10 via a 34-kb deleted-type copy number variation is associated with embryonic mortality
- 负责人：
- 关键词：
- Cancer Space Science Medicine Genetics Evolutionary Biology 69999 Biological Sciences not elsewhere classified 19999 Mathematical Sciences not elsewhere classified Plant Biology Computational Biology
- DOI：
- doi:10.6084/m9.figshare.c.3627914_d6.v1
- 摘要：
- by cows that received a second round of AI at 18\u201329 days (D), 30\u201360 D, 61\u201390 D, 91\u2013140 D, and 141 D\u2013parturition after the 1st AI
Data from: Identifying metabolic subpopulations from population level mass spectrometry
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.gf80t
- 摘要：
- can lead to disease and aging. In addition, metabolic heterogeneity can have biological consequences, such as differences in outcomes and drug
