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Data from: Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
- 负责人：
- DOI：
- doi:10.5061/dryad.mb463
- 摘要：
- Antibiotic resistance is one of the biggest threats to human health globally. Alarmingly, multidrug-resistant and extensively drug-resistant
Data from: Cell death and survival due to cytotoxic exposure modeled as a two-state Ising system
- 负责人：
- DOI：
- doi:10.5061/dryad.4qrfj6q6d
- 摘要：
- is given by an IC50 value. Chemotherapy uses both target-specific and systemic-action drugs and drug combinations to treat cancer. It is importa
LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
- 负责人：
- Eidarus Salah;;Beltrami, Alessandra;;Apirat Chaikuad;;Hanke, Thomas;;Kashima, Risa;;Canning, Peter;;Knapp, Susanne Muller;;Knaus, Petra;;Hata, Akiko
- DOI：
- doi:10.5287/bodleian:zg5naqjyk
- 摘要：
- that may potentially allow the development of a safe drug for this chronic indication.
Data from: “Gaming the System”: a qualitative study on the price of drugs for multiple sclerosis
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.vn5js14
- 摘要：
- and clout of drug distribution and supply channels was also cited as a contributing factor. Although decisions to raise prices were motivated by the nee
Data from: Does high-dose antimicrobial chemotherapy prevent the evolution of resistance?
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.fs950
- 摘要：
- High-dose chemotherapy has long been advocated as a means of controlling drug resistance in infectious diseases but recent empirical studies hav
Data from: The fitness of drug-resistant malaria parasites in a rodent model: multiplicity of infection
- 负责人：
- DOI：
- doi:10.5061/dryad.853nh
- 摘要：
- can have profound effects on the evolution of drug resistance. Here, using the Plasmodium chabaudi mouse malaria model, we ask whether
Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1287260
- 摘要：
- that may potentially allow the development of a safe drug for this chronic indication.;;This document represents version 4 of the TEP datasheet
Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1241027
- 摘要：
- that may potentially allow the development of a safe drug for this chronic indication.;;This document represents version 3 of the TEP datasheet
Human LIM domain kinase 1 (LIMK1), kinase domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1219706
- 摘要：
- that may potentially allow the development of a safe drug for this chronic indication.;;This document represents version 6 of the TEP datasheet
Data from: Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum
- 负责人：
- DOI：
- doi:10.5061/dryad.qb814
- 摘要：
- compete or grow independently. Competition between drug-sensitive and drug-resistant strains, if it occurs, could be a crucial determinant of the spread
