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Data from: The impact of within-host ecology on the fitness of a drug-resistant parasite
负责人:
关键词:
rodent malaria;fitness cost;within-host competition;Drug resistance;malaria;Plasmodium chabaudi
DOI:
doi:10.5061/dryad.1g2n6d2
摘要:
Background and objectives: The rate of evolution of drug resistance depends on the fitness of resistant pathogens. The fitness of resistant pathogens
Data from: Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs
负责人:
关键词:
Neurotransmitter response patterns;Neuropsychiatric drugs;database
DOI:
doi:10.5061/dryad.86088n1
摘要:
, with often insufficient efficacy and undesirable side effects. One reason for this is that the links between molecular drug action and neurobehavioral
Data from: Resource limitation prevents the emergence of drug resistance by intensifying within-host competition
负责人:
关键词:
Mus musculus;combination therapy;competition;Drug resistance;Plasmodium chabaudi
DOI:
doi:10.5061/dryad.v2q3v
摘要:
Slowing the evolution of antimicrobial resistance is essential if we are to continue to successfully treat infectious diseases. Whether a drug
Data from: Self-assembly behaviors of peptide-drug conjugates: influence of multiple factors on aggregate morphology and potential self-assembly
负责人:
关键词:
Peptide-drug conjugates;self-assembly;nanoribbon
DOI:
doi:10.5061/dryad.ft7c7
摘要:
Peptide-drug conjugates (PDCs) as self-assembly prodrugs have the unique and specific features to build one-component nanomedicines
Data from: A critical appraisal of clinical trials conducted and subsequent drug approvals in India and South Africa
负责人:
关键词:
Ethics (see Medical Ethics);Clinical Trials;Protocols & guidelines;1st January 2005 to 31st December 2010
DOI:
doi:10.5061/dryad.013hq
摘要:
Objectives: To assess the relation between the number of clinical trials conducted and respective new drug approvals in India and South Africa.
A study of consumer's attitude toward buying skin care product through drug stores in Thailand
负责人:
James G. Hutton, Advisor
关键词:
Skin care product Drug store Buying decision factors Consumer behavior Consumers\u2019 attitude
DOI:
doi:10.14457/tu.the.2015.893
摘要:
store or drug store to meet with changed of consumer behavior to get the product from reliable channel.To focus on special store (drug store) channel, wha
Data from: Predicting drug-induced liver injury using ensemble learning methods and molecular fingerprints
负责人:
关键词:
DOI:
doi:10.5061/dryad.1k8m6p2
摘要:
Drug-induced liver injury (DILI) is a major safety concern in the drug-development process, and various methods have been proposed to predict
Data from: Aggressive chemotherapy and the selection of drug resistant pathogens
负责人:
关键词:
within-host dynamics;Aggressive treatment;Treatment regime;Evolution;within-host competition;Drug resistance;malaria;Plasmodium chabaudi
DOI:
doi:10.5061/dryad.09qc0
摘要:
Drug resistant pathogens are one of the key public health challenges of the 21st century. There is a widespread belief that resistance is best
Data from: Rapid quantitative pharmacodynamic imaging by a novel method: theory, simulation testing and proof of principle
负责人:
关键词:
fMRI;pharmacological fMRI;pharmacodynamics;phMRI;drug development;EC50;pharmacokinetic-pharmacodynamic modeling;ED50;neuroimaging;dose-finding
DOI:
doi:10.5061/dryad.s3443
摘要:
Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe

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