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Data from: Developmental expression of drug metabolizing enzymes: impact on disposition in neonates and young children
- 负责人：
- DOI：
- doi:10.5061/dryad.71pp6
- 摘要：
- Profound changes in drug metabolizing enzyme expression occurs during development that impacts drug efficacy and the risk of adverse events
Data from: Association between commercial funding of Canadian patient groups and their views about funding of medicines: an observational study
- 负责人：
- DOI：
- doi:10.5061/dryad.th725q8
- 摘要：
- Background: Patient groups represent the interest of their members when it comes to drug funding. Many patient groups receive grants from
Data from: Exploring an alternative explanation for the second phase of viral decay: infection of short-lived cells in a drug-limited compartment
- 负责人：
- DOI：
- doi:10.5061/dryad.6980c06
- 摘要：
- ly. However, significant differences in drug concentrations are observed in monocytes from various tissues, suggesting the first two phases of decay
Data from: Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics
- 负责人：
- DOI：
- doi:10.5061/dryad.03n60
- 摘要：
- Traditional means for scoring the effects of anti-cancer drugs on the growth and survival of cell lines is based on relative cell number in drug
Data from: Decline in new drug launches: myth or reality? Retrospective observational study using 30 years of data from the UK
- 负责人：
- DOI：
- doi:10.5061/dryad.2263n
- 摘要：
- Objective: To describe trends in new drugs launched in the UK from 1982 to 2011 and test the hypothesis that the rate of new drug introductions ha
Data from: Amphotericin B-conjugated polypeptide hydrogels as a novel innovative strategy for fungal infections
- 负责人：
- DOI：
- doi:10.5061/dryad.pc602
- 摘要：
- carriers and the corresponding drug deliveries further help elucidate the molecular arrangement in gel phase, indicating the existence of turn features
Data from: Clinical trial registration, reporting, publication and FDAAA compliance: a cross-sectional analysis and ranking of new drugs approved
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.t8n07
- 摘要：
- l clinical trials submitted to the Food and Drug Administration (FDA) for drugs approved in 2012, sponsored by large biopharmaceutical companies. Data sources: Inf
Data from: How innovative are new drugs launched in the UK? A retrospective study of new drugs listed in the British National Formulary (BNF) 2001
- 负责人：
- DOI：
- doi:10.5061/dryad.pd670
- 摘要：
- lue. Design and setting: Retrospective observational study of new drug entries in the British National Formulary (BNF). Primary and secondary outcome measures
Data from: Evolution of drug-tolerant nematode populations in response to density reduction
- 负责人：
- DOI：
- doi:10.5061/dryad.734c8
- 摘要：
- of resistance, including interactions between life-history traits and the strength of selection imposed by different drug-doses. We experimentally created
Optogenetic control of genetically-targeted pyramidal neuron activity in prefrontal cortex
- 负责人：
- DOI：
- doi:10.6084/m9.figshare.91540.v2
- 摘要：
- Intravenous drug self-administration is the most valid animal model of human addiction because it allows volitional titration of the drug
