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Data from: Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin
- 负责人:
- DOI:
- doi:10.5061/dryad.05c6v93
- 摘要:
- of therapeutics.?Nazartinib?(EGF 816; NAZ) is a new anti-cancer candidate proposed as a third-generation epidermal growth factor rece
Data from: Magnetoliposomes containing magnesium ferrite nanoparticles as nanocarriers for the model drug curcumin
- 负责人:
- DOI:
- doi:10.5061/dryad.482q2rh
- 摘要:
- plications of magnetoliposomes containing MgFe2O4 nanoparticles in cancer therapy, allowing combined magnetic hyperthermia and chemotherapy.
Data from: Global methylation in relation to methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia
- 负责人:
- DOI:
- doi:10.5061/dryad.t3g1vc3
- 摘要:
- and the SAM:SAH ratio did not change significantly. LINE1 DNA methylation (+1.4% (-1.1 - +6.5), p<0.001) increased during therapy. SAM and SAH levels wer
Data from: Comparison of cerebral blood volume and plasma volume in untreated intracranial tumors
- 负责人:
- 关键词:
- DCE-MR imaging;Fractional Plasma Volume;Perfusion;Brain Tumor;Cerebral Blood Volume;DSC-MR Imaging
- DOI:
- doi:10.5061/dryad.7f7d1
- 摘要:
- t common intracranial tumor types. Methods: Twenty-four newly diagnosed, treatment na?ve brain tumor patients, who had undergone DCE- and DSC-MRI, wer
Data from: Mannose glycosylation is an integral step for human NIS localization and function in breast cancer cells
- 负责人:
- DOI:
- doi:10.5061/dryad.r7sqv9s7f
- 摘要:
- its scope for targeted radio-iodine therapy. While developing NIS transgene over-expressing MCF-7 breast adenocarcinoma, a few unique clonal derivatives sh
Data from: Clinical factors associated with long-term complete remission versus poor response to chemotherapy in HIV-infected
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.75tn6
- 摘要:
- and vincristine plus nevirapine-based highly active anti-retroviral therapy (HAART). Median age was 8.6 years (range 1.7–17.9); there were 35 females (50%). Mos
Data from: Anthracycline drugs on modified surface of quercetin-loaded polymer nanoparticles: a dual drug delivery model for cancer treatment
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.5gf06
- 摘要:
- formulate NF1 and NF2 respectively. The sizes of these NFs are in the range 400-500 nm as ascertained by SEM and DLS measurements. Encap
Data from: Immunotherapy-related adverse events (irAEs): extraction from FDA drug labels and comparative analysis
- 负责人:
- DOI:
- doi:10.5061/dryad.fg6kt38
- 摘要:
- ant immune-related adverse events (irAEs) and the underlying biological mechanisms are not well-understood. To ensure safe cancer treatment, research efforts
Data from: Immune checkpoint inhibitor–related myositis and myocarditis in patients with cancer
- 负责人:
- DOI:
- doi:10.5061/dryad.6r19m91
- 摘要:
- patients received immunosuppressive therapy, which consistently led to marked clinical improvement. Conclusions: irMyositis presents with remarkably
Data from: BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains
- 负责人:
- Howard, Kristina E
- 关键词:
- Checkpoint inhibitor BLT-immune humanized mice immunotoxicity pharmaceuticals histopathology toxicity chronic
- DOI:
- doi:10.5061/dryad.99fq552
- 摘要:
- Checkpoint inhibitors represent a new class of therapeutics in the treatment of cancer that have demonstrated remarkable clinical effectiveness