Data from: BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains

负责人：

Howard, Kristina E

关键词：

immunotoxicity Checkpoint inhibitor BLT-immune humanized mice pharmaceuticals histopathology chronic

DOI：

doi:10.5061/dryad.99fq552

摘要：

une-mediated adverse effects of anti-PD1 therapy, and may represent a model that can be used to better understand toxicity of this class of drugs.

Data from: In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish

负责人：

关键词：

Zebrafish;reactive oxygen species (ROS);phagocytes;neutrophil;macrophage;polycyclic aromatic hydrocarbons;Endocrine disrupting chemicals;Acenaphthenequinone;Azathioprine;Benzoapyrene;dexamethasone;Dichloroacetic Acid;17-?-Estradiol;Hydroquinone;Lead acetate (II) trihydrate;Methoxychlor;Phenanthrene;Tributlytin Oxide;trichloroethylene;zebrafish embryo;larval zebrafish;Flow cytometry

DOI：

doi:10.5061/dryad.z8w9ghx86

摘要：

Currently assessment of the potential immunotoxicity of a given agent involves a tiered approach