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Data from: Evaluating in vitro-in vivo extrapolation of toxicokinetics
- 负责人：
- DOI：
- doi:10.5061/dryad.32v7b
- 摘要：
- ve been developed to predict TK, but most of the in vivo TK data available to benchmark these methods are from pharmaceuticals. Here we report on new, in vivo rat TK
Data from: Water-borne pharmaceuticals reduce phenotypic diversity and response capacity of natural phytoplankton communities
- 负责人：
- DOI：
- doi:10.5061/dryad.7rn79
- 摘要：
- h is mediated by the organisms' expressed phenotypic traits. We tested whether exposure to a mixture of 12 pharmaceuticals and personal care products (PPCP
Data from: BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains
- 负责人：
- Howard, Kristina E
- 关键词：
- pharmaceuticals Checkpoint inhibitor BLT-immune humanized mice immunotoxicity histopathology toxicity chronic
- DOI：
- doi:10.5061/dryad.99fq552
- 摘要：
- s, encephalitis, and adrenal or pituitary insufficiency. These adverse events were not predicted by nonclinical studies. To determine if bone marrow-liver
Data from: How innovative are new drugs launched in the UK? A retrospective study of new drugs listed in the British National Formulary (BNF) 2001
- 负责人：
- DOI：
- doi:10.5061/dryad.pd670
- 摘要：
- Objectives: Innovative new drugs offer potential benefits to patients, healthcare systems, governments and the pharmaceutical industry. Recent data
FAIRsharing record for: CDISC Define eXtensible Markup Language;;CDISC Define-XML
- 负责人：
- DOI：
- doi:10.25504/fairsharing.yr61md
- 摘要：
- is required by the United States Food and Drug Administration (FDA) and the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) for every study in eac
Data from: Prozac in the water: chronic fluoxetine exposure and predation risk interact to shape behaviors in an estuarine crab
- 负责人：
- DOI：
- doi:10.5061/dryad.vk3ns
- 摘要：
- ies. This fills an important data gap, highlighting how intra- and interspecific behaviors are altered by exposure to field concentrations of pharmaceuticals; suc
Data from: Clinical study reports of randomised controlled trials: an exploratory review of previously confidential industry reports
- 负责人：
- DOI：
- doi:10.5061/dryad.331f7
- 摘要：
- es total) dated 1991-2011 of 14 pharmaceuticals. Report synopses had a median length of 5 pages, efficacy evaluation 13.5 pages, safety evaluation 17 pag
Data from: An androgenic endocrine disruptor alters male mating behaviour in the guppy (Poecilia reticulata)
- 负责人：
- Bertram, Michael
- 关键词：
- Agricultural pollution Endocrine-disrupting chemical Reproductive behaviour Sexual selection Trenbolone Veterinary pharmaceutical
- DOI：
- doi:10.5061/dryad.gg1839b
- 摘要：
- ity of endocrine-disrupting chemicals (EDCs) to alter reproductive traits, relatively few studies have examined the impacts of EDCs on mechanisms of sexual selection. This study
, clarity, turbidity, isotopes, and pharmaceuticals
- 负责人：
- 关键词：
- DOI：
- doi:10.6073/pasta/ac102e6fed07d1abecf65f28d39e9ed6
- 摘要：
- , clarity, turbidity, isotopes, and pharmaceuticals doi:10.6073/pasta/89eb8f9c94842c3ec0b1e8f80c300e95
, clarity, turbidity, isotopes, and pharmaceuticals
- 负责人：
- 关键词：
- DOI：
- doi:10.6073/pasta/dfaa8b33f8b84ac1dfd947e9d57ccbe6
- 摘要：
- , clarity, turbidity, isotopes, and pharmaceuticals doi:10.6073/pasta/89eb8f9c94842c3ec0b1e8f80c300e95
