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Data from: Effect of lysyl oxidase inhibition on angiotensin II-induced arterial hypertension, remodeling, and stiffness
负责人:
关键词:
Collagen;Aorta;Pulse Wave Velocity;extracellular matrix
DOI:
doi:10.5061/dryad.65525
摘要:
with or without the LOX blocker, ? -aminopropionitrile (BAPN), for 14 days. Pulse wave velocity (PWV) from Doppler measurements of the aortic flow wave was used to quantify
Data from: Single-cell virus sequencing of influenza infections that trigger innate immunity
负责人:
关键词:
10X Chromium;defective virus;influenza virus;single-cell RNA-seq;Interferon;NS1;PacBio;PB1;Heterogeneity
DOI:
doi:10.5061/dryad.nh053c6
摘要:
Influenza-infected cells vary widely in their expression of viral genes, and only occasionally activate innate immunity. Here we develop a new method
Data from: Invasion of Solanum tuberosum L. by Aspergillus terreus: a microscopic and proteomics insight on pathogenicity
负责人:
关键词:
phylogeny Cadmodulin locus maximum likelihood method pathogenicity
DOI:
doi:10.5061/dryad.590j0
摘要:
Background: Aspergillus terreus is one of the most harmful filamentous fungal pathogen of humans, animals and plants. Recently, researchers hav
Data from: Metabolites of n-Butylparaben and iso-Butylparaben exhibit estrogenic properties in MCF-7 and T47D human breast cancer cell lines
负责人:
关键词:
environmental;estrogens;Breast Cancer;endocrine;paraben
DOI:
doi:10.5061/dryad.sm5h0
摘要:
ly. The expression of a pro-proliferative, estrogen-inducible gene (GREB1) was induced by these compounds and blocked by co-administration of an ER antagonist (ICI 182
Data from: Intrinsically regulated learning is modulated by synaptic dopamine signaling
负责人:
关键词:
Reward;Homo Sapiens;memory;levodopa;risperidone;learning;Language;word learning;dopamine
DOI:
doi:10.5061/dryad.g5f7v1j
摘要:
We recently provided evidence that an intrinsic reward-related signal-triggered by successful learning in absence of any external feedback-modulated
Dataset for research paper: α-Synuclein Increases β-Amyloid Secretion by Promoting β-\/γ-Secretase Processing of APP
负责人:
University Of Bath
关键词:
Biochemistry and physiology Cells
DOI:
doi:10.15125/bath-00310
摘要:
-1, Amyloid Precursor Protein β-Secretase Inhibitor (βSI), and β-Secretase Inhibitor IV (βIV) were purchased from Merck Millipore. DAPT was purchased from Tocris. TAPI, βSI, βIV
Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment
负责人:
关键词:
Adrenocortical carcinoma;immunotherapy;humanized mouse PDX model;anti-PD-1
DOI:
doi:10.5061/dryad.f8q4350
摘要:
Context: While the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research model
Data from: Loss of miR-143 and miR-145 in condyloma acuminatum promotes cellular proliferation and inhibits apoptosis by targeting NRAS
负责人:
关键词:
proliferation;miR-143;miR-145;apoptosis;condyloma acuminatum
DOI:
doi:10.5061/dryad.407tq
摘要:
to reduced proliferation, greater apoptosis, and inhibition of expression of NRAS, PI3Kp110?, and pAKT. However, knockout of miR-143 or miR-145 in human
Data from: The effect of atomoxetine on random and directed exploration in humans
负责人:
关键词:
norepinephrine;noradrenergic;directed exploration;foraging task;explore\/exploit;decision noise;gambling task;random exploration;atomoxetine
DOI:
doi:10.5061/dryad.14m41
摘要:
ed atomoxetine, a norepinephrine transporter blocker that increases extracellular levels of norepinephrine throughout the cortex, to 22 healthy human participants
Data from: Identification of reactive intermediate formation and bioactivation pathways in Abemaciclib metabolism by LC–MS/MS: in vitro metabolic
负责人:
关键词:
Abemaciclib;Reactive metabolites;Side effects;Iminium reactive intermediates
DOI:
doi:10.5061/dryad.71f1s18
摘要:
centre in ABC structure helped in making targeted modifications to improve its safty and retain its efficacy. Blocking or isosteric replacement of ? carbon

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