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Data from: Combination phosphodiesterase type 4 inhibitor and phosphodiesterase type 5 inhibitor treatment reduces non-voiding contraction
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- DOI：
- doi:10.5061/dryad.q7n55m2
- 摘要：
- Introduction: Current treatments for overactive bladder (OAB) are often discontinued due to side effects or lack of efficacy. The goal of this study
Data from: Examining the effects of the histone methyltransferase inhibitor BIX-01294 on histone modifications and gene expression in both a clinical
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- DOI：
- doi:10.5061/dryad.15n9404
- 摘要：
- to establish the potential therapeutic value of the HMT inhibitor BIX-01294 (BIX). Human peripheral mononuclear cells (PBMC) from 24 individuals
Data from: The role of metalloproteases in fertilisation in the ascidian Ciona robusta
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- Ciona robusta;biochemistry;sperm;metalloproteases;Ciona robusta (formerly C. intestinalis type A)
- DOI：
- doi:10.5061/dryad.3kc345s
- 摘要：
- during sperm penetration. TALEN-mediated knockout of Tast genes and the presence of GM6001 impaired larval development at the metamorphic stage
The Cat As A Naturally Occurring Model Of Renal Interstitial Fibrosis: Characterisation Of Primary Feline Proximal Tubular Epithelial Cells
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- DOI：
- doi:10.5281/zenodo.1341887
- 摘要：
- stitial inflammation and fibrosis in both species. Cats with CKD may represent a spontaneously occurring, non-rodent animal model of human disease, however littl
The Cat As A Naturally Occurring Model Of Renal Interstitial Fibrosis: Characterisation Of Primary Feline Proximal Tubular Epithelial Cells
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- DOI：
- doi:10.5281/zenodo.1341886
- 摘要：
- stitial inflammation and fibrosis in both species. Cats with CKD may represent a spontaneously occurring, non-rodent animal model of human disease, however littl
Data from: Neuromuscular adverse events associated with Anti-PD-1 monoclonal antibodies: systematic review
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- 关键词：
- Immune checkpoint inhibitor;Myasthenia;Muscle disease;Autoimmune diseases;Peripheral neuropathy
- DOI：
- doi:10.5061/dryad.84q73s8
- 摘要：
- Neuromuscular adverse events following cancer treatment with anti–programmed cell death protein 1 (PD-1) monoclonal antibodies are relatively rare
Data from: Dissociable temporal effects of bupropion on behavioural measures of emotional and reward processing in depression
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- DOI：
- doi:10.5061/dryad.17296
- 摘要：
- Background: Antidepressants remediate negative biases in emotional processing early in treatment, prior to mood improvement. However, the effect
Data from: Analyzing negative feedback using a synthetic gene network expressed in the Drosophila melanogaster embryo
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- DOI：
- doi:10.5061/dryad.68864
- 摘要：
- a localized increase in free Gal4 and therefore signaling. Mathematical modeling was used to demonstrate the capacity for negative feedback to produce these
Data from: Stress hormones mediate predator-induced phenotypic plasticity in amphibian tadpoles
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- DOI：
- doi:10.5061/dryad.1kf76
- 摘要：
- morphological changes induced by predator chemical cue; this predator effect was blocked by the corticosteroid biosynthesis inhibitor metyrapone. Tadpole tail explants
Data from: Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin
- 负责人：
- DOI：
- doi:10.5061/dryad.05c6v93
- 摘要：
- with a postulated electrostatic force-driven interaction. This was further verified by theoretical examination of the NAZ?docking?on the HSA surface that revealed
