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Therapeutic potential of rhesus theta (θ) defensin-1 in cystic fibrosis airway infection and inflammation
- 负责人：
- 关键词：
- Clinical and Experimental Therapeutics cystic fibrosis infection inflammation preclinical drug development
- DOI：
- doi:10.25549/usctheses-c40-309144
- 摘要：
- of ELF concentrations necessary for antibacterial and anti-inflammatory effects. In line with PK data, we observed antibact
Data from: A novel open access web portal for integrating mechanistic and toxicogenomic study results
- 负责人：
- DOI：
- doi:10.5061/dryad.159h65k
- 摘要：
- , leading to relevant mechanistic conclusions. We describe its application by analyzing the effects of several toxicants on liver gene express
Data from: Differential temperature sensitivity of synaptic and firing processes in a neural mass model of epileptic discharges explains
- 负责人：
- DOI：
- doi:10.5061/dryad.vr4sk
- 摘要：
- without affecting the brain’s normal neurological function. Findings suggest a viable treatment for intractable epilepsy cases via an implantable coolin
Data from: Synthesis and characterization of silver nanoparticle-decorated cobalt nanocomposites (Co@AgNPs) and their density-dependent
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.0bk10qf
- 摘要：
- Magnetic cores loaded with metallic nanoparticles can be promising nano-carriers for successful drug delivery at infectious sites. We report
Data from: Postmarket safety in Canada: are significant therapeutic advances and biologics less safe than other drugs? A cohort study
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- DOI：
- doi:10.5061/dryad.fg679
- 摘要：
- Objectives: Examine the probability of new active substances (NASs) approved in Canada between 1 January 1997 and 31 March 2012 acquiring a se
Data from: Age-related differences in bitter taste and efficacy of bitter blockers
- 负责人：
- DOI：
- doi:10.5061/dryad.1jb04
- 摘要：
- ) evaluated the effectiveness of two bitter blockers, sodium gluconate (NaG) and monosodium glutamate (MSG), for five food-grade bitter compounds (quinine
Data from: Medical-device recalls in the UK and the device-regulation process: retrospective review of safety notices and alerts
- 负责人：
- DOI：
- doi:10.5061/dryad.585t4
- 摘要：
- on, and Food and Drug Administration recall system of severity. Results: In total, 2124 field safety notices were issued over the 5-year period, an increase of 1220% (62 in 2006
Data from: Non-industry sponsored preclinical studies on statins yield greater efficacy estimates than industry-sponsored studies: a meta-analysis
- 负责人：
- DOI：
- doi:10.5061/dryad.754d0
- 摘要：
- in a cohort of published preclinical statin studies. We searched Medline (January 1966 - April 2012) and identified 63 studies evaluating the effects
Data from: Enzymatic degradation of liquid droplets of DNA is modulated near the phase boundary
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- 关键词：
- DOI：
- doi:10.25349/D95G66
- 摘要：
- nt for cellular function. Analogous systems are studied as early-life compartmentalization mechanisms, for applications as protocells, or as drug-delivery vehicles. In ma
Data from: Glucagon-like peptide-1 receptor agonist Liraglutide has anabolic bone effects in ovariectomized rats without diabetes
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- 关键词：
- DOI：
- doi:10.5061/dryad.mf3rb
- 摘要：
- ate that the anti-diabetic drug Liraglutide can exert a bone protective effect even in non-diabetic osteoporotic OVX rats. This protective effect is li
