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Data from: Early antiretroviral therapy and potent second-line drugs could decrease HIV incidence of drug resistance
负责人:
关键词:
Second-line drug effectiveness;Early ART initiation;Transmission of drug-resistant HIV;Mathematical model;Acquired drug resistance
DOI:
doi:10.5061/dryad.3v9h5
摘要:
incidence of ART initiation timing, frequency of acquired drug resistance, and second-line drug effectiveness (defined as the combinati
Data from: Evolution of drug-tolerant nematode populations in response to density reduction
负责人:
关键词:
Parasitology;Life History Evolution;Natural Selection and Contemporary Evolution;Caenorhabditis remanei;Experimental evolution;Population Ecology;Adaptation
DOI:
doi:10.5061/dryad.734c8
摘要:
ween life-history stage, selection regime and survival. Intriguingly, both drug-selected and random-mortality lines showed an increase in survivorship when challenged
Data from: The fitness of drug-resistant malaria parasites in a rodent model: multiplicity of infection
负责人:
关键词:
within-host dynamics;selection coefficient;competitive release;multiplicity of infection;competition;Drug resistance;malaria;complexity of infection;Plasmodium chabaudi
DOI:
doi:10.5061/dryad.853nh
摘要:
can have profound effects on the evolution of drug resistance. Here, using the Plasmodium chabaudi mouse malaria model, we ask whether
Data from: Acquisition of conditioning between methamphetamine and cues in healthy humans
负责人:
关键词:
human;CUE;associative learning;preference;Conditioning Strength;Pavlovian Conditioning;Methamphetamine;Attention Bias;Acquisition
DOI:
doi:10.5061/dryad.d2vf8
摘要:
, under double-blind conditions, during 4 hr sessions. MA produced prototypic subjective effects (mood, ratings of drug effects) and alterati
Data from: Modelling the evolution of HIV-1 virulence in response to imperfect therapy and prophylaxis
负责人:
关键词:
art;virulence evolution;set-point viral load;Adaptive dynamics;PrEP
DOI:
doi:10.5061/dryad.26767
摘要:
virulence evolution in response to ‘leaky’ therapy (treat- ment that imperfectly suppresses viral replication) and the use of preventive drugs (pre-exposure prophylaxis
Data from: Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean childr
负责人:
关键词:
P. vivax;primaquine;relapse;cohort;Infection risk
DOI:
doi:10.5061/dryad.m1n03
摘要:
of mass drug administration (MDA) for the prevention of recurrent P. vivax infections. Targeting hypnozoites through PQ treatment reduced the risk of having at least one qPCR
Data from: Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs
负责人:
关键词:
Neurotransmitter response patterns;Neuropsychiatric drugs;database
DOI:
doi:10.5061/dryad.86088n1
摘要:
, with often insufficient efficacy and undesirable side effects. One reason for this is that the links between molecular drug action and ne
Data from: Benefits of an anti-parasite treatment are influenced by within-brood size variation in Tree Swallows (Tachycineta bicolor)
负责人:
关键词:
Tree Swallows ;Tachycineta bicolor; anti-parasite drugs;ivermectin (IVM)
DOI:
doi:10.5061/dryad.zs7h44j51
摘要:
m, anti-parasite drug, ivermectin (IVM), to?treat individual nestling Tree Swallows (Tachycineta bicolor) and assess how nestling susceptibili
Data from: The effect of atomoxetine on random and directed exploration in humans
负责人:
关键词:
norepinephrine;noradrenergic;directed exploration;foraging task;explore\/exploit;decision noise;gambling task;random exploration;atomoxetine
DOI:
doi:10.5061/dryad.14m41
摘要:
uromodulators that are also affected by atomoxetine, or that the reduction in random exploration was driven by a drug-related increase in phasic norepinephrine
Data from: Self-assembly behaviors of peptide-drug conjugates: influence of multiple factors on aggregate morphology and potential self-asse
负责人:
关键词:
Peptide-drug conjugates;self-assembly;nanoribbon
DOI:
doi:10.5061/dryad.ft7c7
摘要:
Peptide-drug conjugates (PDCs) as self-assembly prodrugs have the unique and specific features to build one-component nanomedicines

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