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Data from: Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC
- 负责人：
- DOI：
- doi:10.5061/dryad.67c92vm
- 摘要：
- ee critical physical features of hiPSC-CMs allows identification of all major drug classes affecting contractility with detection sensitivities higher tha
Data from: Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data
- 负责人：
- DOI：
- doi:10.5061/dryad.4539d
- 摘要：
- , we show how the distributions, fitness landscapes, and selection strength of single-cell phenotypes are affected by the drug. Our work provides a unified
Data from: Temperature-sensitive fitness cost of insecticide resistance in Chinese populations of the diamondback moth Plutella xylostella
- 负责人：
- DOI：
- doi:10.5061/dryad.nb5pq
- 摘要：
- ons of the diamondback moth, Plutella xylostella, is conferred by two mutations of ace1 – the gene encoding the acetylcholinesterase enzyme targeted by OPs – affecti
Data from: Diflunisal inhibits prestin by chloride-dependent mechanism
- 负责人：
- DOI：
- doi:10.5061/dryad.vq1dc
- 摘要：
- -binding site on prestin. In a screen to identify other inhibitors of prestin activity, we explored the effect of the non-steroid anti-inflammatory drug
Data from: Anaesthetic interventions for prevention of awareness during surgery
- 负责人：
- 关键词：
- PTSD;anesthesia depth monitors;memory;awareness;implicit memory;explicit memory;wakefulness;BIS
- DOI：
- doi:10.5061/dryad.2vn65
- 摘要：
- s given and reduce the risk of wakefulness and awareness. Anaesthetic drugs have many different effects on brain function. Some drugs are used alone
Data from: Assessment of lung function in successfully treated Tuberculosis reveals high burden of ventilatory defects and COPD
- 负责人：
- DOI：
- doi:10.5061/dryad.1340q4t
- 摘要：
- of lung function defects and COPD in tuberculosis cases who successfully completed treatment. Screening for chronic lung diseases following treatment and lin
Data from: Does high-dose antimicrobial chemotherapy prevent the evolution of resistance?
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.fs950
- 摘要：
- High-dose chemotherapy has long been advocated as a means of controlling drug resistance in infectious diseases but recent empirical studies have
Data from: An experimental analysis of the molecular effects of trastuzumab (herceptin) and fulvestrant (falsodex), as single agents
- 负责人：
- DOI：
- doi:10.5061/dryad.7mp37
- 摘要：
- Purpose: To investigate the effects of trastuzumab (herceptin) and fulvestrant (falsodex) either in combination or alone, on downstream cell signalin
Data from: Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function
- 负责人：
- DOI：
- doi:10.5061/dryad.1rd4hc7
- 摘要：
- Objective: We carried out first-in-patient studies of vamorolone, a first-in-class dissociative steroidal anti-inflammatory drug
Data from: Compensatory mutations improve general permissiveness to antibiotic resistance plasmids
- 负责人：
- DOI：
- doi:10.5061/dryad.v25vk
- 摘要：
- ng multi-drug resistance plasmid RP4, determined plasmid persistence and cost using a joint experimental-modeling approach, resequenced evolved clones, and reconstructed key
