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Data from: Rapid molecular evolution across amniotes of the IIS/TOR network
- 负责人：
- DOI：
- doi:10.5061/dryad.vn872
- 摘要：
- and interventions into disease. The insulin/insulin-like signaling and target of rapamycin (IIS/TOR) molecular network regulates metabolism, growth, and aging
Data from: Glutamatergic drive along the septo-temporal axis of hippocampus boosts prelimbic oscillations in the neonatal mouse
- 负责人：
- DOI：
- doi:10.5061/dryad.52fh7
- 摘要：
- ons is still unresolved. Here, we selectively target optogenetic manipulation of glutamatergic projection neurons in the CA1 area of either dorsal
Data from: Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis
- 负责人：
- DOI：
- doi:10.5061/dryad.8h646s0
- 摘要：
- ences in the gene expression of a downstream target of the Fgfr2 mutation that were associated with Apert syndrome, demonstrating that these mouse models can further
Data from: Hepatocyte-specific deletion of TIPARP, a negative regulator of the aryl hydrocarbon receptor, is sufficient to increase sensiti
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.qd7t1s8
- 摘要：
- y for dioxin-induced liver toxicity. We previously reported that loss of TCDD-inducible poly(ADP-ribose) polymerase (TIPARP/PARP7/ARTD14), an AHR target ge
The E3-ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development.pdf
- 负责人：
- 关键词：
- 60102 Bioinformatics Cell Biology Microbiology Parasitology 60307 Host-Parasite Interactions 60502 Infectious Agents 110309 Infectious Diseases Pathology 60411 Population, Ecological and Evolutionary Genetics 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
- DOI：
- doi:10.6084/m9.figshare.5505661.v1
- 摘要：
- parasite growth. Off target effects were excluded based on restoration of the normal glycan chain and growth upon genetic complementation. By analogy
Data from: A comprehensive mathematical model of motor unit pool organization, surface electromyography and force generation
- 负责人：
- DOI：
- doi:10.5061/dryad.326qs26
- 摘要：
- , which ensures that the model force output equals the desired target force. On a physiological level, this corresponds to adjusting the rate coding mode
Data from: Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production
- 负责人：
- DOI：
- doi:10.5061/dryad.2n3162c
- 摘要：
- -mitochondrial interface for the first time as a viable target for therapeutic intervention.
Data from: Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function.
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.02v6wwq08
- 摘要：
- -directed-repair (HDR)-based gene-editing to enforce FOXP3 expression.? Targeted insertion of a robust enhancer/promoter proximal to the first coding exon
Data from: Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children
- 负责人：
- DOI：
- doi:10.5061/dryad.m1n03
- 摘要：
- al effect of mass drug administration (MDA) for the prevention of recurrent P. vivax infections. Targeting hypnozoites through PQ treatment reduced the risk of having at least one qPCR
Data from: Oxidative stress-mediated NF?B phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival throug
- 负责人：
- DOI：
- doi:10.5061/dryad.2gn8c
- 摘要：
- apolipoprotein E4 targeted-replacement (APOE4) mouse model of AMD was used to study expression of p62 and other autophagy proteins in the retina. p62, NF?B p65 (tota
