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Optogenetic control of genetically-targeted pyramidal neuron activity in prefrontal cortex
- 负责人：
- DOI：
- doi:10.6084/m9.figshare.91540.v2
- 摘要：
- in the blood based on an individual\u2019s motivational state together with the pharmacokinetic properties of the drug. Here we describe a reliable low-cost
Data from: Mind the gap: genetic manipulation of basicranial growth within synchondroses modulates calvarial and facial shape in mice throug
- 负责人：
- DOI：
- doi:10.5061/dryad.35vf4
- 摘要：
- growth that target two very different mechanisms, we show that strong reduction in cartilage growth produces a short, wide, and more flexed cranial base
Data from: Malat1 as an evolutionarily conserved lncRNA, plays a positive role in regulating proliferation and maintaining undifferentiated sta
- 负责人：
- DOI：
- doi:10.5061/dryad.017t8
- 摘要：
- t mouse Malat1 expresses in tissues of liver, kidney, lung, heart, testis, spleen and brain, but not in skeletal muscle. After treating erythroid myeloid
Data from: Multi-omics investigation reveals benzalkonium chloride disinfectants alter sterol and lipid homeostasis in the mouse neonatal brain
- 负责人：
- 关键词：
- Mus musculus
- DOI：
- doi:10.5061/dryad.003vg7g
- 摘要：
- was to use targeted and untargeted mass spectrometry and transcriptomics to investigate the effect of BACs on sterol and lipid homeostasis, and to predict
Data from: Super-resolution imaging of a 2.5 kb non-repetitive DNA in situ in the nuclear genome using molecular beacon probes
- 负责人：
- DOI：
- doi:10.5061/dryad.126k9
- 摘要：
- nomic domains with a resolution limit of 4.9 kb. To target shorter elements, we developed a simple FISH method that uses only molecular beacon (MB) probes
A percutaneously implantable wireless neurostimulator for treatment of stress urinary incontinence
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- 关键词：
- Biomedical Engineering stress urinary incontinence neurostimulation implant wireless pelvic floor muscle training motor axon non-hermetic packaging minimal invasiveness
- DOI：
- doi:10.25549/usctheses-c40-436304
- 摘要：
- challenges. ? We have developed a single channel, monolithic microstimulator (3.5mm diameter * 10 mm long) that can be implanted close to targeted motor axons
Data from: Elovanoids counteract oligomeric ?-Amyloid-induced gene expression and protect photoreceptors
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.59zw3r233
- 摘要：
- ?-induced changes in gene expression engaged in senescence, inflammation, autophagy, extracellular matrix remodeling and AMD. Moreover, since OA? target
Data from: Resource limitation prevents the emergence of drug resistance by intensifying within-host competition
- 负责人：
- DOI：
- doi:10.5061/dryad.v2q3v
- 摘要：
- -susceptible pathogens within the host. Competitive interactions thus represent a good target for resistance management strategies. Using an in vivo model
Data from: Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterati
- 负责人：
- DOI：
- doi:10.5061/dryad.p5614
- 摘要：
- and neuromorphological alterations, but not in the structural alterations found in DS, and suggest that pharmacological strategies targeting this gene may improve
Data from: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates
- 负责人：
- DOI：
- doi:10.5061/dryad.p6261d6
- 摘要：
- oic acid-induced differentiation factor), a previously identified genetic target of N-BPs. SLC37A3 and ATRAID localize to lysosomes and are required for releasing N-BP molecules tha
