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Data from: Association of years to parent’s sporadic onset and risk factors with neural integrity and Alzheimer’s biomarkers
- 负责人：
- DOI：
- doi:10.5061/dryad.280gb5mn1
- 摘要：
- Objective: To evaluate the hypothesis that proximity to parental age at onset (AAO) in sporadic Alzheimer’s disease (AD) is associated with greater
Data from: Site-specific structural order in Alzheimer’s A?42 fibrils
- 负责人：
- DOI：
- doi:10.5061/dryad.768dk4s
- 摘要：
- Deposition of amyloid fibrils is a pathological hallmark of Alzheimer’s disease. A?42 is the major protein whose aggregation leads to the formation
Data from: Body mass index, diet, physical inactivity and the incidence of dementia in one million UK women
- 负责人：
- DOI：
- doi:10.5061/dryad.3s755j8
- 摘要：
- null after 15 years. Conclusions: Mid-life obesity may well be a cause of dementia. In contrast, behavioural changes due to preclinical disease could
Data from: Postmortem neurodegenerative markers and trajectories of decline in cognitive systems
- 负责人：
- DOI：
- doi:10.5061/dryad.mf7hk2q
- 摘要：
- th, they underwent a neuropathologic examination to quantify Alzheimer’s disease (AD) pathology, Lewy bodies, transactive response DNA-binding protein 43 (TDP-43
Data from: Increased CAIDE dementia risk, cognition, CSF biomarkers and vascular burden in healthy adults
- 负责人：
- DOI：
- doi:10.5061/dryad.0f454q8
- 摘要：
- Objective: To investigate the cognitive profile of healthy individuals with increased CAIDE dementia risk score, and to explore whether
Data from: Microglial activation in early Alzheimer trajectory is associated with higher grey matter volume
- 负责人：
- DOI：
- doi:10.5061/dryad.6mp3r21
- 摘要：
- Objective: To investigate the influence of microglial activation in the early stages of Alzheimer’s disease trajectory, we assessed the relationship
Data from: ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes
- 负责人：
- DOI：
- doi:10.5061/dryad.88br3tn
- 摘要：
- Objective. The amyloid/tau/neurodegeneration (ATN) research framework for Alzheimer’s disease (AD) was proposed to organize AD biomarker
Data from: Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with DTI MRI
- 负责人：
- DOI：
- doi:10.5061/dryad.121hs31
- 摘要：
- h as Alzheimer's disease.
Circadian and brain state modulation of network hyperexcitability in Alzheimer's disease - rodent datasets
- 负责人：
- University Of Edinburgh;;University Of Edinburgh
- DOI：
- doi:10.7488/ds/2319
- 摘要：
- Network hyperexcitability is a feature of Alzheimer's disease (AD) as well as numerous transgenic mouse models of AD. While hyperexcitability in AD
Data from: Low-dose proton radiation effects in a transgenic mouse model of Alzheimer's Disease - implications for space travel
- 负责人：
- Vlkolinsky, Roman
- 关键词：
- Mice Electrophysiology Animal behavior Protons Hippocampus Brain electrophysiology Alzheimer's disease Cytokines
- DOI：
- doi:10.5061/dryad.0008d
- 摘要：
- ts neuronal functions such as excitability, synaptic transmission, and plasticity, and it may accelerate the onset of Alzheimer's disease (AD). Although protons
