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Data from: Big data analysis of genes associated with neuropsychiatric disorders in an Alzheimer's disease animal model
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.408d6f0
- 摘要：
- Alzheimer’s disease is a neurodegenerative disease characterized by the impairment of cognitive function and loss of memory, affecting millions
Data from: An MRI measure of degenerative and cerebrovascular pathology in Alzheimer’s disease
- 负责人：
- DOI：
- doi:10.5061/dryad.m8s3r88
- 摘要：
- Objective: To develop, replicate, and validate an MRI-based quantitative measure of both cerebrovascular and neurodegeneration in Alzheimer’s disease
Data from: The Alzheimer’s comorbidity phenome: mining from a large patient database and phenome-driven genetics prediction
- 负责人：
- 关键词：
- disease comorbidity;Alzheimer\u2019s disease;Systems biology;disease genetics discovery;data mining
- DOI：
- doi:10.5061/dryad.3p9b4c2
- 摘要：
- Objective: Alzheimer’s disease (AD) is a severe neurodegenerative disorder and has become a global public health problem. Intensive research ha
Data from: Revisiting protein aggregation as pathogenic in sporadic Parkinson’s and Alzheimer’s diseases
- 负责人：
- Espay, Alberto J.
- 关键词：
- Parkinson’s disease Alzheimer’s disease biomarkers disease modifying treatments clinical trials
- DOI：
- doi:10.5061/dryad.g1nq02r
- 摘要：
- es and for Alzheimer’s disease (AD) aggregated amyloid into plaques and hyperphosphorylated tau into tangles. Implicit in this clinico-pathologic-based nosology
Data from: Sex differences in CSF biomarkers vary by Alzheimer’s disease stage and APOE epsilon 4 genotype
- 负责人：
- DOI：
- doi:10.5061/dryad.ttdz08ktw
- 摘要：
- Objective:? To evaluate sex-differences in cerebrospinal fluid (CSF) biomarkers, taking the potential modifying role of clinical disease stage
Data from: The effect of funding sources on donepezil randomised controlled trial outcome: a meta-analysis
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.1h18h
- 摘要：
- Objective: To investigate whether there is a difference in the treatment effect of donepezil on cognition in Alzheimer disease between industry
Data from: ApoE is a correlate of phenotypic heterogeneity in Alzheimer’s disease in a national cohort
- 负责人：
- DOI：
- doi:10.5061/dryad.69qg1c0
- 摘要：
- Objective: To compare the proportion of APOE?4 genotype carriers in aphasic versus amnestic variants of Alzheimer’s disease (AD). Method
Data from: Antiepileptic drug use and mortality among community-dwelling persons with Alzheimer’s disease
- 负责人：
- DOI：
- doi:10.5061/dryad.q3b38p9
- 摘要：
- Objective: To evaluate the risk of death in relation to incident antiepileptic drug use compared with non-use in people with Alzheimer’s disease (AD
Data from: Distinct epileptiform abnormalities are associated with clinical seizures in Alzheimer’s disease
- 负责人：
- DOI：
- doi:10.5061/dryad.8gtht76kc
- 摘要：
- Objective: Examine the relationship between scalp EEG biomarkers of hyperexcitability in Alzheimer’s disease (AD) and determine how these electrical
Data from: Total A?42/A?40 ratio in plasma predict amyloid-PET status, independent of clinical AD diagnosis
- 负责人：
- DOI：
- doi:10.5061/dryad.f300d56
- 摘要：
- Background: Research has focussed upon the identification of a blood-based biomarker to inform clinicians on the likelihood of Alzheimer’s disease
