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Population pharmacokinetic\/pharmacodynamic modeling: evaluation of maximum likelihood expectation maximization method in ADAPT 5
- 负责人:
- 关键词:
- Biomedical Engineering population PK\/PD maximum likelihood expectation maximization IVGTT minimal model ADAPT
- DOI:
- doi:10.25549/usctheses-m143
- 摘要:
- Unrestricted Maximum likelihood estimation via the expectation maximization algorithm (EML) was implemented into ADAPT 5 to support population
Data from: Comparing evolutionary rates between trees, clades, & traits
- 负责人:
- DOI:
- doi:10.5061/dryad.5st8m
- 摘要:
- nt a simple, likelihood-based method for comparing the rate of phenotypic evolution for continuous characters between trees. Our method is derived from
Data from: Bayesian adaptive Markov Chain Monte Carlo estimation of genetic parameters
- 负责人:
- 关键词:
- Hordeum vulgare L.
- DOI:
- doi:10.5061/dryad.0p88f
- 摘要:
- to be practically zero, which was in agreement with the support from the likelihood (in the case of no dominance). The method performance is illustrated usi
Data from: Inferring bounded evolution in phenotypic characters from phylogenetic comparative data
- 负责人:
- DOI:
- doi:10.5061/dryad.k974s
- 摘要:
- ry different kind. We provide analytical expressions for the likelihood of BBM and present a method to calculate the likelihood numerically
Data from: Maximum likelihood inference of small trees in the presence of long branches
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.rp7qv
- 摘要:
- The statistical basis of maximum likelihood (ML), its robustness and the fact that it appears to suffer less from biases lead to it being one
Data from: EMMLi: a maximum likelihood approach to the analysis of modularity
- 负责人:
- DOI:
- doi:10.5061/dryad.091v0
- 摘要:
- an skull. Here, we present a maximum likelihood approach that takes into account model parameterization. We compare model log-likelihood
Data from: Quantifying age-dependent extinction from species phylogenies
- 负责人:
- DOI:
- doi:10.5061/dryad.7894h
- 摘要:
- esent here a computational framework to quantify age-dependent extinction through maximum likelihood parameter estimation based on phylogenetic trees
Data from: Complex models of sequence evolution require accurate estimators as exemplified with the invariable site plus Gamma model
- 负责人:
- DOI:
- doi:10.5061/dryad.4j5c7
- 摘要:
- The invariable site plus ? model is widely used to model rate heterogeneity among alignment sites in maximum likelihood and Bayesian
Data from: Assessing parameter identifiability in phylogenetic models using Data Cloning
- 负责人:
- DOI:
- doi:10.5061/dryad.rr6400b4
- 摘要:
- e, we illustrate how Data Cloning (DC), a recently developed methodology to compute the Maximum Likelihood estimates along with their asymptotic variance, can be use
Data from: The shape of modern tree reconstruction methods
- 负责人:
- DOI:
- doi:10.5061/dryad.22d26
- 摘要:
- of phylogenetic trees, inferred tree shapes can be compared to expectations under probabilistic models of speciation and extinction in an attempt to ma