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Population pharmacokinetic\/pharmacodynamic modeling: evaluation of maximum likelihood expectation maximization method in ADAPT 5
负责人:
关键词:
Biomedical Engineering population PK\/PD maximum likelihood expectation maximization IVGTT minimal model ADAPT
DOI:
doi:10.25549/usctheses-m143
摘要:
Unrestricted Maximum likelihood estimation via the expectation maximization algorithm (EML) was implemented into ADAPT 5 to support population
Data from: Comparing evolutionary rates between trees, clades, & traits
负责人:
关键词:
Comparative Methods;Phrynosomatinae;maximum likelihood;phylogeny;Liolaemini
DOI:
doi:10.5061/dryad.5st8m
摘要:
nt a simple, likelihood-based method for comparing the rate of phenotypic evolution for continuous characters between trees. Our method is derived from
Data from: Bayesian adaptive Markov Chain Monte Carlo estimation of genetic parameters
负责人:
关键词:
Hordeum vulgare L.
DOI:
doi:10.5061/dryad.0p88f
摘要:
to be practically zero, which was in agreement with the support from the likelihood (in the case of no dominance). The method performance is illustrated usi
Data from: Inferring bounded evolution in phenotypic characters from phylogenetic comparative data
负责人:
关键词:
bounds;Macroevolution;evolutionary constraints;BBM;maximum-likelihood estimation;phylogenetic comparative data
DOI:
doi:10.5061/dryad.k974s
摘要:
ry different kind. We provide analytical expressions for the likelihood of BBM and present a method to calculate the likelihood numerically
Data from: Maximum likelihood inference of small trees in the presence of long branches
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关键词:
DOI:
doi:10.5061/dryad.rp7qv
摘要:
The statistical basis of maximum likelihood (ML), its robustness and the fact that it appears to suffer less from biases lead to it being one
Data from: EMMLi: a maximum likelihood approach to the analysis of modularity
负责人:
关键词:
Mammals;Morphological Evolution;phenotypic integration;model selection;Macaca fuscata;trait correlations
DOI:
doi:10.5061/dryad.091v0
摘要:
an skull. Here, we present a maximum likelihood approach that takes into account model parameterization. We compare model log-likelihood
Data from: Quantifying age-dependent extinction from species phylogenies
负责人:
关键词:
coalescent point process;Macroevolution;phylogenetics;diversification;Solanaceae;Aves;maximum likelihood estimation
DOI:
doi:10.5061/dryad.7894h
摘要:
esent here a computational framework to quantify age-dependent extinction through maximum likelihood parameter estimation based on phylogenetic trees
Data from: Complex models of sequence evolution require accurate estimators as exemplified with the invariable site plus Gamma model
负责人:
关键词:
Gamma model;phylogenetic inference;maximum likelihood;rate heterogeneity among sites;invariable sites
DOI:
doi:10.5061/dryad.4j5c7
摘要:
The invariable site plus ? model is widely used to model rate heterogeneity among alignment sites in maximum likelihood and Bayesian
Data from: Assessing parameter identifiability in phylogenetic models using Data Cloning
负责人:
关键词:
Data Cloning;Bayesian estimation in Phylogenetics;Parameter Identifiability;maximum likelihood
DOI:
doi:10.5061/dryad.rr6400b4
摘要:
e, we illustrate how Data Cloning (DC), a recently developed methodology to compute the Maximum Likelihood estimates along with their asymptotic variance, can be use
Data from: The shape of modern tree reconstruction methods
负责人:
关键词:
bayesian analysis;tree shape;parsimony;maximum likelihood
DOI:
doi:10.5061/dryad.22d26
摘要:
of phylogenetic trees, inferred tree shapes can be compared to expectations under probabilistic models of speciation and extinction in an attempt to ma

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