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Data from: Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and r
- 负责人：
- Lammens, Lieve
- DOI：
- doi:10.5061/dryad.5vv774m
- 摘要：
- ; Findings: Safety pharmacology, toxicity and genotoxicity studies have been conducted with the flubendazole ASD formulation. In animals, flubendazole ha
Data from: Phylogeny meets ecotoxicology: evolutionary patterns of sensitivity to a common insecticide
- 负责人：
- DOI：
- doi:10.5061/dryad.q2mf26f1
- 摘要：
- Pesticides commonly occur in aquatic systems and pose a substantial challenge to the conservation of many taxa. Ecotoxicology has traditionally met
Cylindrospermopsin toxicity in mice following a 90-d oral exposure
- 负责人：
- 关键词：
- Biochemistry Cell Biology Genetics Pharmacology 59999 Environmental Sciences not elsewhere classified 39999 Chemical Sciences not elsewhere classified Marine Biology 60506 Virology
- DOI：
- doi:10.6084/m9.figshare.6182216.v1
- 摘要：
- . Toxicity included effects indicative of both hepatic and renal dysfunction. In humans, symptoms progressed from initial hepatomegaly, vomiting, and malaise
Data from: A novel open access web portal for integrating mechanistic and toxicogenomic study results
- 负责人：
- DOI：
- doi:10.5061/dryad.159h65k
- 摘要：
- Applying toxicogenomics to improving the safety profile of drug candidates and crop protection molecules is most useful when it identifies relevant
Data from: Digestive capacity and toxicity cause mixed diets in red knots that maximize energy intake rate
- 负责人：
- DOI：
- doi:10.5061/dryad.5fp4g
- 摘要：
- ies to maximize energy intake. The model correctly predicted the preferences of the captive birds, which depended on the digestive quality and toxicity of thei
Data from: Multi-behavioral endpoint testing of an 87-chemical compound library in freshwater planarians
- 负责人：
- Zhang, Siqi
- 关键词：
- DOI：
- doi:10.5061/dryad.mk6m608
- 摘要：
- There is an increased recognition in the field of toxicology of the value of medium-to-high-throughput screening methods using in vitro
Data from: Application of benchmark concentration (BMC) analysis on zebrafish data – a new perspective for quantifying toxicity in alternative
- 负责人：
- 关键词：
- Danio rerio
- DOI：
- doi:10.5061/dryad.rt7f0b0
- 摘要：
- Over the past decade, the zebrafish is increasingly being used as a model to screen for chemical-mediated toxicities including developmental toxicity
Data from: Thermal evolution offsets the elevated toxicity of a contaminant under warming: a resurrection study in Daphnia magna
- 负责人：
- DOI：
- doi:10.5061/dryad.kh6jg77
- 摘要：
- l stressor: zinc oxide nanoparticles (nZnO) in a natural population of Daphnia magna using resurrection ecology. We hatched resting eggs from two D. magna
Data from: Ageratina adenophora causes spleen toxicity by inducing oxidative stress and pyroptosis in mice
- 负责人：
- Hu, Yanchun
- DOI：
- doi:10.5061/dryad.gf2np70
- 摘要：
- Ageratina adenophora (A. adenophora) is an invasive weed with potent toxicological effects on livestock. Oxidative stress and pyroptosis play
Data from: Hepatocyte-specific deletion of TIPARP, a negative regulator of the aryl hydrocarbon receptor, is sufficient to increase sensitivity
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.qd7t1s8
- 摘要：
- , steatohepatitis, and a lethal wasting syndrome in laboratory rodents. Although the mechanisms of dioxin toxicity remain unknown, AHR signaling in hepatocytes is nec
