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Data from: Hepatoprotective effect of wheat-based solid-state fermented Antrodia cinnamomea in carbon tetrachloride-induced liver injury in rat
- 负责人:
- DOI:
- doi:10.5061/dryad.p066m
- 摘要:
- solid-state fermented A. cinnamomea (WFAC) to protect against carbon tetrachloride (CCl4)-induced hepatic injury in vivo. The results showed tha
Data from: From the cover: three-dimensional (3d) heparg spheroid model with physiologically relevant xenobiotic metabolism competence and hepatocyte
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.s05v3
- 摘要:
- pharmacologically- and environmentally important hepatic receptor pathways (ie AhR, CAR, and PXR) analogous to primary human hepatocyte cultures. HepaRG spheroid
Data from: Acetaminophen responsive miR-19b modulates SIRT1/Nrf2 signaling pathway in drug-induced hepatotoxicity
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.sm12b53
- 摘要:
- P-induced hepatic liver injury in mice. Furthermore, APAP responsive miR-19b played an important role in regulating SIRT1 expression, whereas overexpression
Data from: Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury
- 负责人:
- DOI:
- doi:10.5061/dryad.g8143
- 摘要:
- A hallmark of acute hepatic injury is the recruitment of neutrophils, monocytes and lymphocytes, including natural killer (NK) or T cells, towards ar
Data from: Nrf2 ameliorates DDC-induced sclerosing cholangitis and biliary fibrosis and improves the regenerative capacity of the liver.
- 负责人:
- Fragoulis, Athanassios
- DOI:
- doi:10.5061/dryad.d8vs845
- 摘要:
- nt for the expression of the hepatic efflux transporters Abcg2 and Abcc2-4, which are involved in hepatic toxin elimination. Surprisingly, cell proliferation was mor
Data from: Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending
- 负责人:
- DOI:
- doi:10.5061/dryad.3n39r6k
- 摘要:
- of drug-induced liver injury, but nothing is known concerning environmental pollutants. We aimed to study the impact of polycyclic aromatic hydrocarbons (PAHs), major
Data from: Prospective randomized trial comparing hepatic venous outflow and renal function after conventional versus piggyback liver transplantation
- 负责人:
- DOI:
- doi:10.5061/dryad.7b9v3
- 摘要:
- onal with venovenous bypass (n = 15) or piggyback (n = 17) liver transplantation. Methods: Free hepatic vein pressure (FHVP) and central venous pressure (CVP
Cylindrospermopsin toxicity in mice following a 90-d oral exposure
- 负责人:
- 关键词:
- Biochemistry Cell Biology Genetics Pharmacology 59999 Environmental Sciences not elsewhere classified 39999 Chemical Sciences not elsewhere classified Marine Biology 60506 Virology
- DOI:
- doi:10.6084/m9.figshare.6182216.v1
- 摘要:
- (i.p.) route of administration and confirmed this pattern of toxicity with changes in liver enzyme activities and histopathology consistent with hepatic injury and adverse renal
Data from: Acute liver dysfunction after cardiac arrest
- 负责人:
- DOI:
- doi:10.5061/dryad.qv6fp83
- 摘要:
- Few data are available regarding hypoxic hepatitis (HH) and acute liver failure (ALF) in patients resuscitated from cardiac arrest (CA). The aim
Data from: Deleterious consequences of antioxidant supplementation on lifespan in a wild-derived mammal
- 负责人:
- DOI:
- doi:10.5061/dryad.31cc4
- 摘要:
- on for 9 months reduced hepatic lipid peroxidation, but DNA oxidative damage to hepatocytes and lymphocytes was unaffected. Surprisingly, anti