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Data from: The relationship between risk of bias criteria, research outcomes, and study sponsorship in a cohort of preclinical thiazolidinedi
- 负责人：
- DOI：
- doi:10.5061/dryad.4c2bj
- 摘要：
- Introduction: There is little evidence regarding the influence of conflicts of interest on preclinical research. This study examines whether
Data from: Non-industry sponsored preclinical studies on statins yield greater efficacy estimates than industry-sponsored studies: a meta-analysis
- 负责人：
- DOI：
- doi:10.5061/dryad.754d0
- 摘要：
- in the methods used. However, the influence of sponsorship bias has not been examined in preclinical animal studies. We performed a meta-analysis of preclinical
Data from: Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials
- 负责人：
- DOI：
- doi:10.5061/dryad.32q9q5d
- 摘要：
- Objective: To revise the 1999 Airlie House consensus guidelines for the design and implementation of preclinical therapeutic studies
Analysis and visualization of multi-mode optical spectral-signature bioimaging data for in vivo applications
- 负责人：
- 关键词：
- Biomedical Engineering multi-mode imaging spectral signature imaging hyperspectral imaging fluorescence lifetime imaging
- DOI：
- doi:10.25549/usctheses-m809
- 摘要：
- in vivo imaging.; The usefulness of our new image analysis and visualization methods is demonstrated for selected preclinical research cases, including rat nec
Data from: Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.44j0zpc9v
- 摘要：
- b preclinical pharmacology data support its therapeutic potential in CDK9- or CDK2-dependent cancers and as a rational combination with BCL2 inhibitors
Data from: Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and r
- 负责人：
- Lammens, Lieve
- DOI：
- doi:10.5061/dryad.5vv774m
- 摘要：
- on these results, in combination with previously described genotoxicity and reproductive toxicity data and the outcome of the preclinical efficacy studies
FAIRsharing record for: CDISC Define eXtensible Markup Language;;CDISC Define-XML
- 负责人：
- DOI：
- doi:10.25504/fairsharing.yr61md
- 摘要：
- is required by the United States Food and Drug Administration (FDA) and the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) for every study in ea
Data from: A systems toxicology approach for the prediction of kidney toxicity and its mechanisms in vitro
- 负责人：
- DOI：
- doi:10.5061/dryad.646v2r1
- 摘要：
- dated by their ability to accurately predict kidney toxicity of 4 out of 6 candidate therapeutics that exhibited toxicity only in in late stage preclinical
FAIRsharing record for: Reporting guidElines For randomized controLled trials for livEstoCk and food safeTy;;REFLECT
- 负责人：
- DOI：
- doi:10.25504/fairsharing.tv1yg0
- 摘要：
- st. It is an evolving document that is subject to change periodically as new evidence emerges.;;The source of this description is the metadata record on FAIRsharing.org
Data from: Distinct BOLD fMRI responses of capsaicin-induced thermal sensation reveal pain-related brain activation in nonhuman primates
- 负责人：
- Asad, Abu Bakar Ali
- DOI：
- doi:10.5061/dryad.2gp4g
- 摘要：
- preclinical research to clinical investigation. Many behavioral and self-report studies of pain have exploited the use of the capsaicin pain model
