Therapeutic potential of rhesus theta (θ) defensin-1 in cystic fibrosis airway infection and inflammation

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关键词：

Clinical and Experimental Therapeutics cystic fibrosis infection inflammation preclinical drug development

DOI：

doi:10.25549/usctheses-c40-309144

摘要：

. Preliminary efficacy studies showed treatment significantly reduced bacterial burden in infected mice. ? Chronic lung infections in CF are associated with

Data from: Cognition at age 70: life course predictors and associations with brain pathologies

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关键词：

Neuropsychological assessment;Alzheimer\u2019s disease;Cognitive aging

DOI：

doi:10.5061/dryad.nt561v7

摘要：

Objective: To investigate predictors of performance on a range of cognitive measures including the Preclinical Alzheimer Cognitive Composite (PACC

Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment

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关键词：

Adrenocortical carcinoma;immunotherapy;humanized mouse PDX model;anti-PD-1

DOI：

doi:10.5061/dryad.f8q4350

摘要：

in a newly generated preclinical model and correlate with the response of the matched patient. Design, Setting and Intervention: To characterize the CU-ACC2