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Data from: Lower extremity muscle pathology in myotonic dystrophy type 1 assessed by quantitative MRI
- 负责人：
- DOI：
- doi:10.5061/dryad.4nb96c1
- 摘要：
- volumes (779±247 cm3 vs. 1054±246 cm3), and increased T2water (33.4±1.0 ms vs. 31.9±0.6 ms), indicating atrophy and oedema, respectively. Lower leg muscles
Data from: Optimizing mouse surgery with online rectal temperature monitoring and preoperative heat supply. Effects on post-ischemic
- 负责人：
- DOI：
- doi:10.5061/dryad.4v131
- 摘要：
- variability, which further correlated with the degree of kidney atrophy 5 weeks after surgery. Changing temperature control setup A to C was equivalent to 10
Data from: Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the HDHQ150/Q150
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.51110
- 摘要：
- o indicating significant atrophy. A hypothesis-free analysis using tensor-based morphometry highlighted further regions undergoing atrophy by contrasting brain
Data from: Nusinersen in later-onset spinal muscular atrophy: long-term results from the phase 1/2 studies
- 负责人：
- 关键词：
- Clinical Trials;Developmental disorders;pediatric;Neuromuscular Disease;Spinal muscular atrophy
- DOI：
- doi:10.5061/dryad.n37q406
- 摘要：
- Objective: Report results of intrathecal nusinersen in children with later-onset spinal muscular atrophy (SMA). Methods: Analyses included children
Data from: Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost
- 负责人：
- Salin, Karine
- DOI：
- doi:10.5061/dryad.v0vg627
- 摘要：
- of reactive oxygen species (ROS). 4. After a 2-week period of fasting, brown trout reduced their whole-liver mitochondrial respiratory capacities (state 3, stat
Data from: Clinical Reasoning: Pes cavus and neuropathy: think beyond Charcot-Marie-Tooth disease
- 负责人：
- DOI：
- doi:10.5061/dryad.876r5m5
- 摘要：
- contractures and pes cavus. She had mild lower limb spasticity without atrophy or fasciculations, and 5?/5 weakness of distal extremity muscles, including
Data from: Loss of paraplegin drives spasticity rather than ataxia in a cohort of 241 patients with SPG7
- 负责人：
- DOI：
- doi:10.5061/dryad.sb4kr01
- 摘要：
- Objective: We took advantage of a large multinational recruitment to delineate genotype-phenotype correlations in a large, trans-European multicenter
Data from: BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains
- 负责人：
- Howard, Kristina E
- 关键词：
- Checkpoint inhibitor BLT-immune humanized mice immunotoxicity pharmaceuticals histopathology toxicity chronic
- DOI：
- doi:10.5061/dryad.99fq552
- 摘要：
- ritis, dermatitis and adrenalitis also noted in some individuals. Additional histopathologic findings included pancreatic atrophy, myositis, and osteomyelitis in som
Data from: Sociosexual and communication deficits after traumatic injury to the developing murine brain
- 负责人：
- DOI：
- doi:10.5061/dryad.2ds7p
- 摘要：
- ulted in a similar degree of atrophy of the corpus callosum by adulthood. However, loss of hippocampal tissue was greater after p21 compared to p35
Data from: Hepatocyte-specific deletion of TIPARP, a negative regulator of the aryl hydrocarbon receptor, is sufficient to increase sensitivity
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.qd7t1s8
- 摘要：
- The aryl hydrocarbon receptor (AHR) mediates the toxic effects of dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDD), which include thymic atrophy
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