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Data from: Immune checkpoint inhibitor–related myositis and myocarditis in patients with cancer
- 负责人:
- DOI:
- doi:10.5061/dryad.6r19m91
- 摘要:
- Objective: To report the clinicopathological features and outcome of myositis in patients treated with immune checkpoint inhibitors (irMyositis
Data from: BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains
- 负责人:
- Howard, Kristina E
- 关键词:
- Checkpoint inhibitor BLT-immune humanized mice immunotoxicity pharmaceuticals histopathology toxicity chronic
- DOI:
- doi:10.5061/dryad.99fq552
- 摘要:
- Checkpoint inhibitors represent a new class of therapeutics in the treatment of cancer that have demonstrated remarkable clinical effectivene
Data from: Immunotherapy-related adverse events (irAEs): extraction from FDA drug labels and comparative analysis
- 负责人:
- DOI:
- doi:10.5061/dryad.fg6kt38
- 摘要:
- Objectives: Immune checkpoint inhibitors (ICIs) have dramatically improved outcomes in cancer patients. However, ICIs are associated with significant
Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment
- 负责人:
- DOI:
- doi:10.5061/dryad.f8q4350
- 摘要:
- Context: While the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research
Data from: Neuromuscular adverse events associated with Anti-PD-1 monoclonal antibodies: systematic review
- 负责人:
- 关键词:
- Immune checkpoint inhibitor;Myasthenia;Muscle disease;Autoimmune diseases;Peripheral neuropathy
- DOI:
- doi:10.5061/dryad.84q73s8
- 摘要:
- treatment strategies including corticosteroid, IV immunoglobulins, and plasma exchange. The clinical presentation of NMDs associated with PD-1 inhibitors is oft
Data from: Landscape of tumor mutation load, mismatch repair deficiency, and PD-L1 expression in a large patient cohort of gastrointestinal cancers
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.qt3v0t4
- 摘要:
- Purpose: The efficacy of immunotherapy varies widely among different gastrointestinal cancers. Response to immune checkpoint inhibitors is sh
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