Data from: Immune checkpoint inhibitor–related myositis and myocarditis in patients with cancer

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关键词：

immune related adverse events;PD-L1;Muscle disease;CTLA-4;PD-1

DOI：

doi:10.5061/dryad.6r19m91

摘要：

Objective: To report the clinicopathological features and outcome of myositis in patients treated with immune checkpoint inhibitors (irMyositis

Data from: Immunotherapy-related adverse events (irAEs): extraction from FDA drug labels and comparative analysis

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关键词：

Checkpoint inhibitors;Immunotherapy-related adverse events;data analysis;Cancer Immunotherapy;Information extraction

DOI：

doi:10.5061/dryad.fg6kt38

摘要：

Objectives: Immune checkpoint inhibitors (ICIs) have dramatically improved outcomes in cancer patients. However, ICIs are associated with significant

Data from: BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains

负责人：

Howard, Kristina E

关键词：

Checkpoint inhibitor BLT-immune humanized mice immunotoxicity pharmaceuticals histopathology toxicity chronic

DOI：

doi:10.5061/dryad.99fq552

摘要：

Checkpoint inhibitors represent a new class of therapeutics in the treatment of cancer that have demonstrated remarkable clinical effec

Data from: Neuromuscular adverse events associated with Anti-PD-1 monoclonal antibodies: systematic review

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关键词：

Immune checkpoint inhibitor;Myasthenia;Muscle disease;Autoimmune diseases;Peripheral neuropathy

DOI：

doi:10.5061/dryad.84q73s8

摘要：

treatment strategies including corticosteroid, IV immunoglobulins, and plasma exchange. The clinical presentation of NMDs associated with PD-1 inhibitors is oft

Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment

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关键词：

Adrenocortical carcinoma;immunotherapy;humanized mouse PDX model;anti-PD-1

DOI：

doi:10.5061/dryad.f8q4350

摘要：

Context: While the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research

Data from: Landscape of tumor mutation load, mismatch repair deficiency, and PD-L1 expression in a large patient cohort of gastrointestinal cancers

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关键词：

DOI：

doi:10.5061/dryad.qt3v0t4

摘要：

Purpose: The efficacy of immunotherapy varies widely among different gastrointestinal cancers. Response to immune checkpoint inhibitors is sh