An aspiration prevention system may be configured to keep items from moving from a mouth of a patient into a throat of the patient. The system may include a mouth prop, a frame, and an air-permeable barrier. The mouth prop may have a top surface configured to abut top teeth of the mouth, a bottom surface configured to abut bottom teeth of the mouth, and a frame coupling feature. The frame may have a barrier retention feature configured to retain an air-permeable barrier, and a prop coupling feature that is attachable to the frame coupling feature of the mouth prop in a position in which the frame at least partially covers the throat.