Childrens Medical Center Corporation;Children's Medical Center Corporation
发明人:
Fiorina, Paolo
申请号：
AU2016296741
公开号：
AU2016296741A1
申请日:
2016.07.20
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Embodiments disclosed here provide engineered modified hematopoietic stem cells (HSCs), artificially prostaglandin E2 (PGE2)-stimulated HSCs, compositions comprising these HSCs, methods of using these modified HSCs for treating autoimmune diseases and disorders and for suppressing the immune system. In particular, the engineered modified HSCs or PGE2-stimulated HSCs express the surface marker, programmed cell death-1 ligand 1 (PD-L1).
