PD-L1 EXPRESSING HEMATOPOIETIC STEM CELLS AND USES

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专利权人:

The Children's Medical Center Corporation

发明人:

Paolo Fiorina

申请号：

US15745553

公开号：

US20180214487A1

申请日:

2016.07.20

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Embodiments disclosed here provide engineered modified hematopoietic stem cells (HSCs), artificially prostaglandin E2 (PGE2)-stimulated HSCs, compositions comprising these HSCs, methods of using these modified HSCs for treating autoimmune diseases and disorders and for suppressing the immune system. In particular, the engineered modified HSCs or PGE2-stimulated HSCs express the surface marker, programmed cell death-1 ligand 1 (PD-L1).

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中国工程科技知识中心

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http://www.ckcest.cn/home/