THE CHILDRENS MEDICAL CENTER CORPORATION;THE CHILDREN'S MEDICAL CENTER CORPORATION
发明人:
申请号：
IL25704618
公开号：
IL257046D0
申请日:
2018.01.21
申请国别(地区):
IL
年份:
2018
代理人:
摘要：
Embodiments disclosed here provide engineered modified hematopoietic stem cells (HSCs), artificially prostaglandin E2 (PGE2)-stimulated HSCs, compositions comprising these HSCs, methods of using these modified HSCs for treating autoimmune diseases and disorders and for suppressing the immune system. In particular, the engineered modified HSCs or PGE2-stimulated HSCs express the surface marker, programmed cell death-1 ligand 1 (PD-L1).
