NZ 597694 Disclosed is an isolated human antibody molecule, as defined in the complete specification. The disclosed antibody: binds to mouse and rat IGF-1 and IGF-2； does not bind to human insulin； and binds to human IGF-1 and IGF-2 such that: binding of IGF-1 and IGF-2 to the IGF-1 receptor is prevented； and IGF-1 receptor-mediated signalling is inhibited. The disclosed antibody is used in the treatment of cancer.
