GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
CROTTS, GEORGE,MORAR-MITRICA, SORINA
申请号：
CA2898262
公开号：
CA2898262A1
申请日:
2014.01.22
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention provides liquid formulations comprising antigen binding proteins which bind specifically to TNF-alpha and histidine buffer. For example novel variants of anti-TNF antibodies such as adalimumab which show increased binding to the FcRn receptor or increased half life compared to adalimumab. Also provided are compositions comprising the antigen binding proteins and uses of such compositions in treatment of disorders and disease.
