GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
George H. CROTTS,Sorina MORAR-MITRICA
申请号：
US14762948
公开号：
US20150368333A1
申请日:
2014.01.22
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides antigen binding proteins which bind specifically to TNF-alpha. For example novel variants of anti-TNF antibodies such as adalimumab which show increased binding to the FcRn receptor or increased half life compared to adalimumab. Also provided are compositions comprising the antigen binding proteins and uses of such compositions in treatment of disorders and disease.
