Mendiratta Sanjeev Kumar,Bandyopadhyay Sanjay,Patel Chintan G.
申请号：
NZ62926113
公开号：
NZ629261A
申请日:
2013.03.05
申请国别(地区):
NZ
年份:
2017
代理人:
摘要：
Disclosed is a liquid pharmaceutical formulation comprising an antibody directed to TNFα in a buffer system with a pH between 4 to 8, a surfactant, a tonicity agent and a stabilizer wherein: the antibody is adalimumab and is present at a concentration of 1 mg / mL to 100 mg / mL； the buffer system is selected from citrate-buffers, succinate-buffers, acetate- buffers, phosphate-buffers, phosphate buffered saline, citrate and phosphate buffer, tromethamine buffers, histidine-buffers, and suitable mixtures thereof； and the stabilizer is an amino acid or combination of amino acids.
